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Clenbuterol

Clen · Beta-2 agonist (fat loss / stimulant-adjacent)

Research reference only. Pepdex does not sell, supply or track this compound, and nothing here is guidance to use it — this page exists so the evidence and the risks are visible.

What it is

A veterinary bronchodilator (and asthma drug in some countries) misused for fat loss. It raises metabolic rate through beta-2 receptor stimulation at exposures asthma medicine never uses.

What human evidence shows

Human asthma data proves the mechanism; livestock data documents the repartitioning effect. Controlled fat-loss trials in healthy humans do not exist — the practice runs entirely on veterinary pharmacology plus community lore.

Risks

Cardiac by mechanism, not by accident: tremors, tachycardia, arrhythmias, and documented myocardial injury case reports — including in young, otherwise healthy users. Can cause hypokalemia (the cramps are a warning, not an inconvenience); taurine depletion reported in animal studies has not been established clinically in humans. Long half-life (~36 h) means a stimulant that never clocks out; poison-control literature features it regularly.

Stacking interactions

Documented interactions with other things people research. A compound not listed here does not mean the combination is safe — only that no specific interaction is on file.

CautionAdderall

Concurrent exposure to agents with sympathomimetic cardiovascular effects may further increase heart rate, blood pressure, or arrhythmia risk; pair-specific evidence varies.

CautionDMAA

Concurrent exposure to agents with sympathomimetic cardiovascular effects may further increase heart rate, blood pressure, or arrhythmia risk; pair-specific evidence varies.

CautionThyroid hormones (T3 / T4)

Concurrent exposure to agents with sympathomimetic cardiovascular effects may further increase heart rate, blood pressure, or arrhythmia risk; pair-specific evidence varies.

CautionTesofensine

Concurrent exposure to agents with sympathomimetic cardiovascular effects may further increase heart rate, blood pressure, or arrhythmia risk; pair-specific evidence varies.

CautionCaffeine

Concurrent exposure to agents with sympathomimetic cardiovascular effects may further increase heart rate, blood pressure, or arrhythmia risk; pair-specific evidence varies.

Legal status

US: not a controlled substance but not approved for human use; certain uses in food-producing animals are prohibited. Banned by WADA.

Evidence base

A2,163 research papers
established literature

Strong human evidence: either a phase 3 or 4 trial report alongside review-level evidence, or ten or more randomised controlled trial reports.

phase 3/4
0
randomised
44
reviews
7
human trials
105

Counts are of published papers, not distinct trials, and measure how much research exists — not whether this works or is safe for you.

Research (12)

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Where next

Every compound in the catalogThe full non-peptide index, with evidence grades.→The peptide indexInjectable peptides, half-lives and what trials used.→Spotting a scam vendorRed flags, COA checks and what traceability looks like.→