News

Compounded tirzepatide is being phased out as Lilly's supply normalizes. Pricing and availability through compounding pharmacies will keep tightening through Q3. If you've been on compounded tirz, plan a transition to Mounjaro/Zepbound coverage or to tirzepatide research-grade through your existing channels.

Per-mg pricing on research-grade reta has fallen ~40% since late 2025 as more vendors stock it ahead of the regulatory submission. If you're on reta, you're likely paying less per cycle now than 6 months ago. Check the welcome-email vendor list for current rates.

Most-asked support ticket lately. Three things help: (1) drop a titration step, (2) eat smaller meals lower in fat, (3) try a digestive bitters supplement before meals. The burps fade for most users by week 6-8 if you push through.

Lyophilized (powder) peptides go in the freezer for long-term, fridge for short-term. Reconstituted (mixed) peptides go in the fridge only — never freeze them once water's been added. The Storage guide has the per-peptide stability windows.

Oral BPC-157 has good data for gut applications (the original use case). For tendon and ligament healing, injectable near the injury site outperforms oral by a wide margin in animal models and user reports. Pick the route that matches your goal.

Phase 3 readouts continue to support the combination over semaglutide alone for users plateaued on GLP-1 monotherapy. Effect size is meaningful but not Tirzepatide-tier. Worth knowing if you've stalled on Wegovy.

Three patterns from members: (1) inject in the evening so you sleep through the worst of it, (2) hold each titration step for 5 weeks instead of 4 if nausea is severe, (3) eat protein and electrolytes — undereating protein makes the fatigue feel like everything else.