Masteron
Drostanolone / Mast / dromostanolone · Anabolic steroid (injectable)
What it is
A DHT-derived injectable with a historical role as a breast-cancer drug (as dromostanolone). Modern non-medical use occurs in physique-sport settings.
What human evidence shows
Real oncology history, zero physique-use trials. Every claim about its cosmetic effect is community anecdote without a controlled measurement behind it.
Risks
Strong androgenic pressure — hair loss and acne are heavily reported — plus lipid damage, HPG-axis suppression, and cardiovascular strain. In practice it is usually taken alongside other AAS, so real-world exposure is rarely to this drug alone.
Legal status
US: Schedule III anabolic steroid under the CSA. No current US pharmaceutical production.
Evidence base
emerging literature
Real human evidence: randomised trial reports, or review-level evidence backed by at least one human trial report.
- phase 3/4
- 0
- randomised
- 4
- reviews
- 0
- human trials
- 5
Counts are of published papers, not distinct trials, and measure how much research exists — not whether this works or is safe for you.
Research (12)
- Exploring the Polymorphism of Drostanolone PropionateMolecules · 2020
- New drostanolone metabolites in human urine by liquid chromatography time-of-flight tandem mass spectrometry and their application for doping controlSteroids · 2016
- Seven new metabolites of drostanolone heptanoate by using Beauveria bassiana, and Macrophomina phaseolina cell suspension culturesRSC Adv · 2019
- Drostanolone and norethisterone in disseminated breast cancerDrug Ther Bull · 1969
- Searching for new long-term urinary metabolites of metenolone and drostanolone using gas chromatography-mass spectrometry with a focus on non-hydrolysed sulfatesDrug Test Anal · 2020
- Treatment of advanced breast carcinoma with drostanolone propionate. A case reportBristol Med Chir J · 1970
- [Drostanolone propionate (masteril) in disseminated breast cancer in women. Immediate results]Khirurgiia (Sofiia) · 1987
- Effect of drostanolone propionate on the binding of oestradiol and dihydrotestosterone by normal and malignant target tissuesEur J Cancer (1965) · 1977
- Identification of drostanolone and 17-methyldrostanolone metabolites produced by cryopreserved human hepatocytesSteroids · 2009
- Intracerebroventricular self-administration of commonly abused anabolic-androgenic steroids in male hamsters (Mesocricetus auratus): nandrolone, drostanolone, oxymetholone, and stanozololBehav Neurosci · 2005
- Comparison of testosterone decanoate, drostanolone and testololactone in disseminated breast cancer--a randomized clinical studyArch Geschwulstforsch · 1975
- [Experiences with Drostanolone-Propionate (Masterid) in metastasizing breast carcinoma]Ther Ggw · 1972
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