Is IGF-1 LR3 legal?
IGF-1 LR3 is not FDA approved as a finished drug. For drug-tested athletes it is WADA banned (S2). Increlex prescribed by pediatric endocrinology for IGF-1 deficiency. IGF-1 LR3 is not prescribed.. Legal status depends on your country and changes over time. This reflects US status at the time of writing and is not legal or medical advice.
Regulatory status
- FDA: Mecasermin (Increlex) approved 2005 for severe primary IGF-1 deficiency. IGF-1 LR3 specifically (research analog) is NOT FDA approved.
- WADA: Banned (S2)
- Prescription: Increlex prescribed by pediatric endocrinology for IGF-1 deficiency. IGF-1 LR3 is not prescribed.
References
- IGF-I and its analogs in clinical use — Clemmons DR, Endocrinol Metab Clin North Am, 2012
- Detection of His-tagged Long-R3-IGF-I in a black market product — Kohler M, Thomas A, Walpurgis K, et al., Growth Hormone & IGF Research, 2010
- Site-specific fluorescent derivatization and liquid chromatographic-mass spectrometric characterization of long R(3) IGF-I for bioanalytical applications — Harvey MD, Banks PR, Journal of Chromatography B, 2003
Pepdex is an editorial reference, not medical advice. Peptides vary in legal and approval status by country, many are research compounds without full human safety data. Talk to a qualified clinician before starting anything.
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Last updated 2026-06-06.