What is the half-life of Teriparatide?
Teriparatide has a reported half life of ~1 hour, given subcutaneous. That is why it is typically dosed once daily. A shorter half life means more frequent dosing to keep blood levels steady, a longer one lets you space doses further apart.
Quick facts
- Half-life: ~1 hour
- Route: Subcutaneous
- Typical schedule: Once daily
- Cycle length: ~24 months standard (FDA removed the hard lifetime cap in 2020)
References
- Effect of Teriparatide on the risk of fractures in postmenopausal women with osteoporosis — Neer RM et al., NEJM, 2001
- Effects of teriparatide and risedronate on new fractures in post-menopausal women with severe osteoporosis (VERO): a multicentre, double-blind, double-dummy, randomised controlled trial — Kendler DL, Marin F, Geusens P, et al. — The Lancet, 2018
- FORTEO (teriparatide) injection — FDA Prescribing Information — FDA / DailyMed (Eli Lilly and Company)
Pepdex is an editorial reference, not medical advice. Peptides vary in legal and approval status by country, many are research compounds without full human safety data. Talk to a qualified clinician before starting anything.
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Last updated 2026-06-06.