What is the half-life of AOD-9604?
AOD-9604 has a reported half life of ~30 minutes, given subcutaneous. That is why it is typically dosed once daily, fasted. A shorter half life means more frequent dosing to keep blood levels steady, a longer one lets you space doses further apart.
Quick facts
- Half-life: ~30 minutes
- Route: Subcutaneous
- Typical schedule: Once daily, fasted
- Cycle length: 8-12 weeks
References
- Metabolic studies of a synthetic lipolytic domain (AOD9604) of human growth hormone — Ng FM, Sun J, Sharma L, et al., Hormone Research, 2000
- The effects of human GH and its lipolytic fragment (AOD9604) on lipid metabolism following chronic treatment in obese mice and beta(3)-AR knock-out mice — Heffernan M, Summers RJ, Thorburn A, et al., Endocrinology, 2001
- Safety and Tolerability of the Hexadecapeptide AOD9604 in Humans — Stier H, Vos E, Kenley D, Journal of Endocrinology and Metabolism, 2013;3(1-2):7-15
Pepdex is an editorial reference, not medical advice. Peptides vary in legal and approval status by country, many are research compounds without full human safety data. Talk to a qualified clinician before starting anything.
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Last updated 2026-06-06.