What is the half-life of DSIP?
DSIP has a reported half life of ~7 minutes (rapidly metabolized), given subcutaneous, pre-bed. That is why it is typically dosed nightly. A shorter half life means more frequent dosing to keep blood levels steady, a longer one lets you space doses further apart.
Quick facts
- Half-life: ~7 minutes (rapidly metabolized)
- Route: Subcutaneous, pre-bed
- Typical schedule: Nightly
- Cycle length: 2-4 weeks at a time
References
- Effects of delta-sleep-inducing peptide on 24-hour sleep-wake behaviour in severe chronic insomnia — Schneider-Helmert D. European Neurology, 1987
- Delta sleep-inducing peptide (DSIP): a still unresolved riddle — Kovalzon VM, Strekalova TV. Journal of Neurochemistry, 2006
Pepdex is an editorial reference, not medical advice. Peptides vary in legal and approval status by country, many are research compounds without full human safety data. Talk to a qualified clinician before starting anything.
More on DSIP
Last updated 2026-06-06.