What is the half-life of HGH (Somatropin)?
HGH (Somatropin) has a reported half life of ~3-5 hours injected, given subcutaneous. That is why it is typically dosed daily. A shorter half life means more frequent dosing to keep blood levels steady, a longer one lets you space doses further apart.
Quick facts
- Half-life: ~3-5 hours injected
- Route: Subcutaneous
- Typical schedule: Daily
- Cycle length: Long-term in medical use
References
- Growth Hormone Treatment in Adults with Growth Hormone Deficiency (clinical practice guideline) — Molitch ME et al., JCEM, 2011
- The effects of treatment with recombinant human growth hormone on body composition and metabolism in adults with growth hormone deficiency — Salomon F, Cuneo RC, Hesp R, et al., New England Journal of Medicine, 1989
- Effects of human growth hormone in men over 60 years old — Rudman D, Feller AG, Nagraj HS, et al., New England Journal of Medicine, 1990
Pepdex is an editorial reference, not medical advice. Peptides vary in legal and approval status by country, many are research compounds without full human safety data. Talk to a qualified clinician before starting anything.
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Last updated 2026-06-06.