What is the half-life of Kisspeptin-10?
Kisspeptin-10 has a reported half life of ~4 minutes (kisspeptin-10), given subcutaneous. That is why it is typically dosed as needed or 1-2x daily during a short cycle. A shorter half life means more frequent dosing to keep blood levels steady, a longer one lets you space doses further apart.
Quick facts
- Half-life: ~4 minutes (kisspeptin-10)
- Route: Subcutaneous
- Typical schedule: As needed or 1-2x daily during a short cycle
- Cycle length: Short bursts; not for chronic use
References
- Kisspeptin in human reproductive health and disease — Skorupskaite K et al., Hum Reprod Update, 2014
- Kisspeptin-54 stimulates the hypothalamic-pituitary gonadal axis in human males — Dhillo WS, Chaudhri OB, Thompson EL, et al.; Journal of Clinical Endocrinology & Metabolism; 2005
- Kisspeptin-10 is a potent stimulator of LH and increases pulse frequency in men — George JT, Veldhuis JD, Roseweir AK, et al.; Journal of Clinical Endocrinology & Metabolism; 2011
Pepdex is an editorial reference, not medical advice. Peptides vary in legal and approval status by country, many are research compounds without full human safety data. Talk to a qualified clinician before starting anything.
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Last updated 2026-06-06.