What is the half-life of Semax?
Semax has a reported half life of ~30 minutes (intranasal), given intranasal spray (sub-q also used). That is why it is typically dosed 1-3x daily. A shorter half life means more frequent dosing to keep blood levels steady, a longer one lets you space doses further apart.
Quick facts
- Half-life: ~30 minutes (intranasal)
- Route: Intranasal spray (sub-q also used)
- Typical schedule: 1-3x daily
- Cycle length: 2-4 weeks on, equal time off
References
- Effectiveness of semax in acute period of hemispheric ischemic stroke (a clinical and electrophysiological study) — Gusev EI, Skvortsova VI, Miasoedov NF, et al. Zh Nevrol Psikhiatr Im S S Korsakova, 1997
- Semax and Pro-Gly-Pro Activate the Transcription of Neurotrophins and Their Receptor Genes after Cerebral Ischemia — Dmitrieva VG, Povarova OV, Skvortsova VI, Limborska SA, Myasoedov NF, Dergunova LV. Cellular and Molecular Neurobiology, 2009
Pepdex is an editorial reference, not medical advice. Peptides vary in legal and approval status by country, many are research compounds without full human safety data. Talk to a qualified clinician before starting anything.
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Last updated 2026-06-06.