What is the half-life of Survodutide?
Survodutide has a reported half life of ~6 days, given subcutaneous. That is why it is typically dosed once weekly. A shorter half life means more frequent dosing to keep blood levels steady, a longer one lets you space doses further apart.
Quick facts
- Half-life: ~6 days
- Route: Subcutaneous
- Typical schedule: Once weekly
- Cycle length: Open-ended, titrate over months
References
- Survodutide for treatment of obesity, Phase 2 trial — le Roux CW et al., Lancet Diabetes Endocrinol, 2024
- A Phase 2 Randomized Trial of Survodutide in MASH and Fibrosis — Sanyal et al., N Engl J Med, 2024
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Last updated 2026-06-15.