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5-HTP

5-hydroxytryptophan / Griffonia extract · Sleep

LimitedLittle human data, early, small, or narrow.

The direct serotonin precursor, sold for mood, sleep and appetite.

What the evidence says

Small old trials on depression and appetite; sleep data is thin.

What studies used

Trials commonly use 50-300 mg per day.. Evening for sleep; with meals for appetite..

Reported from published studies and product labelling — a record of what was used in research, not a recommendation. What is right for you is a conversation with a clinician.

Watch out for

  • Never combine with antidepressants, tramadol or MAOIs (serotonin syndrome)
  • Nausea is common

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