Alpha-lipoic acid
ALA / R-lipoic acid / thioctic acid · Metabolic
An antioxidant with real trial data for diabetic nerve pain and a weaker case for glucose and weight.
What the evidence says
600 mg daily improved diabetic neuropathy symptoms across several trials; weight and glucose effects are small.
What studies used
Trials commonly use 600 mg per day; labels list 300-600 mg.. On an empty stomach, per most labels..
Reported from published studies and product labelling — a record of what was used in research, not a recommendation. What is right for you is a conversation with a clinician.
Watch out for
- Can lower blood sugar alongside diabetes drugs
- Thiamine deficiency risk with heavy alcohol use
- Take apart from thyroid medication
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