Myo-inositol
Metabolic
Sugar alcohol studied mainly in PCOS for insulin sensitivity and cycle regularity.
What the evidence says
A reasonable human trial base specifically in PCOS. Evidence outside that population is much thinner.
What studies used
2–4 g daily, often with D-chiro-inositol. Split through the day.
Reported from published studies and product labelling — a record of what was used in research, not a recommendation. What is right for you is a conversation with a clinician.
Evidence base
established literature
Large human evidence base: several phase 3 or 4 trial reports, plus multiple meta-analyses or systematic reviews.
This letter measures how much human research exists, not whether it works for you — the tier above (Moderate) is the read on quality.
Research (12)
- Myo-Inositol and D-Chiro-Inositol as Modulators of Ovary Steroidogenesis: A Narrative ReviewNutrients · 2023
- Inositol Treatment for PCOS Should Be Science-Based and Not ArbitraryInt J Endocrinol · 2020
- From Myo-inositol to D-chiro-inositol molecular pathwaysEur Rev Med Pharmacol Sci · 2021
- Phosphate, inositol and polyphosphatesBiochem Soc Trans · 2016
- Production of myo-inositol: Recent advance and prospectiveBiotechnol Appl Biochem · 2022
- Inositol Phosphates and Synthesizing Enzymes: Implications in Neurodegenerative DisordersBiomolecules · 2025
- 1-Deoxy-1-[(18)F]fluoro-scyllo-inositol2004
- The use of D-chiro-Inositol in clinical practiceEur Rev Med Pharmacol Sci · 2021
- Myo-Inositol and Its Derivatives: Their Emerging Role in the Treatment of Human DiseasesFront Pharmacol · 2019
- [Myo-inositol]Nihon Rinsho · 1998
- Inositol and human reproduction. From cellular metabolism to clinical useGynecol Endocrinol · 2016
- The role of inositol in the environmental organic phosphate cycleCurr Opin Biotechnol · 2024
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