Enteric peppermint oil
Gut
Antispasmodic studied specifically for IBS pain and bloating.
What the evidence says
Several human RCTs and meta-analyses support it for IBS symptoms. Enteric coating matters — uncoated causes reflux.
What studies used
180–225 mg enteric-coated, 2–3× daily in trials. Before meals.
Reported from published studies and product labelling — a record of what was used in research, not a recommendation. What is right for you is a conversation with a clinician.
Watch out for
- Uncoated capsules commonly cause heartburn
Evidence base
established literature
Strong human evidence: either a phase 3 or 4 trial report alongside review-level evidence, or ten or more randomised controlled trial reports.
This letter measures how much human research exists, not whether it works for you — the tier above (Moderate) is the read on quality.
Research (12)
- The Use of Peppermint Oil in GastroenterologyCurr Pharm Des · 2023
- [Peppermint oil in the acute treatment of tension-type headache]Schmerz · 2016
- Systematic review and meta-analysis: efficacy of peppermint oil in irritable bowel syndromeAliment Pharmacol Ther · 2022
- Peppermint oilAm Fam Physician · 2007
- Peppermint oil for the treatment of irritable bowel syndrome: a systematic review and meta-analysisJ Clin Gastroenterol · 2014
- Efficacy and Safety of Peppermint Oil in a Randomized, Double-Blind Trial of Patients With Irritable Bowel SyndromeGastroenterology · 2020
- Review article: the physiological effects and safety of peppermint oil and its efficacy in irritable bowel syndrome and other functional disordersAliment Pharmacol Ther · 2018
- An Overview of Commonly Used Natural Alternatives for the Treatment of Androgenetic Alopecia, with Special Emphasis on Rosemary OilClin Cosmet Investig Dermatol · 2024
- Peppermint oil-associated hepatotoxicityJ Hepatol · 2025
- The Effects of Peppermint Oil on Nausea, Vomiting and Retching in Cancer Patients Undergoing Chemotherapy: An Open Label Quasi-Randomized Controlled Pilot StudyComplement Ther Med · 2021
- Peppermint oilPediatr Rev · 2006
- A review of the bioactivity and potential health benefits of peppermint tea (Mentha piperita L.)Phytother Res · 2006
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