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Saccharomyces boulardii

S. boulardii / Florastor · Gut

ModerateSeveral human trials, smaller or less consistent.

A probiotic yeast, not a bacterium, with the best evidence of any probiotic for antibiotic and traveler's diarrhea.

What the evidence says

Meta-analyses show fewer antibiotic-associated diarrhea cases; it survives antibiotics because it is a yeast.

What studies used

Trials commonly use 250-500 mg (5-10 billion CFU) once or twice daily.. During and after a course of antibiotics; before and during travel..

Reported from published studies and product labelling — a record of what was used in research, not a recommendation. What is right for you is a conversation with a clinician.

Watch out for

  • Fungal infection risk with central lines or severe immune suppression
  • Yeast allergy

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