Tirzepatide reconstitution & dose calculator

Enter your Tirzepatide vial size, the BAC water you added and your dose to see the units to draw on a U-100 insulin syringe.

Tirzepatide vial size

BAC water you added

Your dose

From the chart below:

Syringe (U-100)

How often

Strength of your mix

5 mg/mL

Enter your dose to see the units to draw.

Strength: 5 mg/mL
1 unit holds: 50 mcg

How long will it last?

Tirzepatide reconstitution chart: units to draw by vial size and BAC water

Find the row for the mg on your vial and the water you added. Amounts are the 2.5 mg steps on the Mounjaro and Zepbound labels, from the 2.5 mg starting dose to the 15 mg maximum. Units are on a U-100 insulin syringe, where 100 units is 1 mL.

If your vial is already liquid, there is nothing to add. Use the total mg in the vial and its volume in mL: a 2 mL vial at 10 mg/mL is the 20 mg row with 2 mL.

Tirzepatide reconstitution chart, units to draw on a U-100 insulin syringe
Vial	BAC water	Strength	Units to draw for
Vial	BAC water	Strength	2.5 mg	5 mg	7.5 mg	10 mg	12.5 mg	15 mg
5 mg	1 mL	5 mg/mL	50	100	more than the vial	more than the vial	more than the vial	more than the vial
	2 mL	2.5 mg/mL	100	200^*	more than the vial	more than the vial	more than the vial	more than the vial
	3 mL	1.67 mg/mL	150^*	300^*	more than the vial	more than the vial	more than the vial	more than the vial
10 mg	1 mL	10 mg/mL	25	50	75	100	more than the vial	more than the vial
	2 mL	5 mg/mL	50	100	150^*	200^*	more than the vial	more than the vial
	3 mL	3.33 mg/mL	75	150^*	225^*	300^*	more than the vial	more than the vial
15 mg	1 mL	15 mg/mL	16.7	33.3	50	66.7	83.3	100
	2 mL	7.5 mg/mL	33.3	66.7	100	133.3^*	166.7^*	200^*
	3 mL	5 mg/mL	50	100	150^*	200^*	250^*	300^*
20 mg	1 mL	20 mg/mL	12.5	25	37.5	50	62.5	75
	2 mL	10 mg/mL	25	50	75	100	125^*	150^*
	3 mL	6.67 mg/mL	37.5	75	112.5^*	150^*	187.5^*	225^*
30 mg	1 mL	30 mg/mL	8.33	16.7	25	33.3	41.7	50
	2 mL	15 mg/mL	16.7	33.3	50	66.7	83.3	100
	3 mL	10 mg/mL	25	50	75	100	125^*	150^*
60 mg	1 mL	60 mg/mL	4.17	8.33	12.5	16.7	20.8	25
	2 mL	30 mg/mL	8.33	16.7	25	33.3	41.7	50
	3 mL	20 mg/mL	12.5	25	37.5	50	62.5	75

* Over 100 units: more than a 1 mL syringe holds in one draw. † Under 2 units: hard to measure; more water makes the draw bigger. Arithmetic from the numbers in each row. Pepdex does not pick a dose for you.

What to know about Tirzepatide before you mix it

Tirzepatide is a dual GIP and GLP-1 receptor agonist, the same molecule as the brand-name drugs Mounjaro and Zepbound.

How it is supplied: Mounjaro and Zepbound come as ready-to-use liquid in pens and single-dose vials, so there is nothing to mix. Reconstitution math only applies to a freeze-dried powder vial.
Common vial sizes: 10 mg, 30 mg. Work from the mg printed on your own vial.
Half-life: About 5 days, which is why it is a once-a-week shot.
Usual schedule on our page: Once weekly.
FDA status: Approved as Mounjaro (2022, type 2 diabetes) and Zepbound (2023, obesity).
Evidence in one line: Greater weight loss than semaglutide, head-to-head. Source: NEJM 2025, SURMOUNT-5 (PMID 40353578).

What people track with Tirzepatide

The amount at each 2.5 mg step and the date you moved up
Weight once a week, at the same time of day
Where each shot went (stomach, thigh or upper arm) so you rotate sites

The common Tirzepatide mix-up

Treating mg and units as the same thing. Labels and steps are in mg; the syringe reads in units. 2.5 mg is 25 units only when the mix is 10 mg per mL, such as 10 mg in 1 mL. From a 10 mg vial mixed with 2 mL, the same 2.5 mg is 50 units.

Full Tirzepatide entry: evidence, side effects, FDA and WADA status

How long a Tirzepatide vial lasts

A 10 mg vial at 2.5 mg a shot holds 4 shots. Taken once a week, that is about 4 weeks. If your amount steps up before the vial is used up, it runs out sooner. Shots per vial for each size:

Shots per Tirzepatide vial at each amount
Vial	At 2.5 mg	At 5 mg	At 7.5 mg	At 10 mg	At 12.5 mg	At 15 mg
5 mg	2 shots	1 shot	under 1	under 1	under 1	under 1
10 mg	4 shots	2 shots	1 shot	1 shot	under 1	under 1
15 mg	6 shots	3 shots	2 shots	1 shot	1 shot	1 shot
20 mg	8 shots	4 shots	2 shots	2 shots	1 shot	1 shot
30 mg	12 shots	6 shots	4 shots	3 shots	2 shots	2 shots
60 mg	24 shots	12 shots	8 shots	6 shots	4 shots	4 shots

Work out the days and weeks for your own vial

Tirzepatide reconstitution questions

How much BAC water (reconstitution solution) do I add to a 10 mg Tirzepatide vial?: Any amount works for the math; it only changes the strength. 10 mg in 1 mL is 10 mg/mL, in 2 mL 5 mg/mL, and in 3 mL 3.33 mg/mL. More water gives a bigger draw that is easier to read. If your product came with mixing directions, those set the volume.
How many units is 2.5 mg of Tirzepatide?: It depends on how much water is in the vial. From a 10 mg vial mixed with 2 mL, 2.5 mg is 50 units (0.5 mL). With 1 mL it is 25 units; with 3 mL, 75 units.
How many 2.5 mg doses are in a 10 mg Tirzepatide vial?: 4. Taken once a week, that lasts about 4 weeks. If the amount steps up before the vial is used up, it runs out sooner. The water you add does not change the count, only the size of each draw.
Is tirzepatide the same as semaglutide?: No. Semaglutide acts on one receptor (GLP-1); tirzepatide acts on two (GIP and GLP-1). They are different molecules, and a dose of one is not a dose of the other.
How do you mix tirzepatide with reconstitution solution?: Only a powder vial is mixed. Wipe the stopper, add the bacteriostatic water slowly down the inside wall of the vial, and let the powder dissolve without shaking. The amount you add sets the concentration, so write it on the vial. If your product came with its own diluent or directions, follow those instead. Mounjaro and Zepbound are already liquid and are never mixed.

Related calculators

Retatrutide reconstitution calculator Semaglutide reconstitution calculator

How long will my vial last?How to reconstitute (full guide)Peptide reconstitution chart (all peptides)

Educational reference. Pepdex does not sell peptides or recommend vendors. The calculator and charts convert amounts into syringe units; whether an amount is right for you is a question for a qualified provider.