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ALCAR (Acetyl-L-Carnitine)

Acetylated L-Carnitine. Crosses the blood-brain barrier. The cognitive sibling of L-Carnitine — same shuttle role plus a brain layer.

What it actually is

Not a peptide. ALCAR is L-Carnitine with an acetyl group attached, which lets it cross the blood-brain barrier where regular L-Carnitine can't go efficiently. The acetyl group also serves as a precursor for acetylcholine in cholinergic neurons.

Why peptide users come across it

Common in nootropic stacks. Used alongside Semax/Selank or as a solo cognitive primer. Often paired with ALA (alpha-lipoic acid) for the senior-aging-brain protocols popularized by the Bruce Ames lab.

Mechanism

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Documented dose range

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Side effects

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Contraindications

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The Pepdex take

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