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№ 019

Selank

Russian-origin synthetic peptide. Anxiolytic and cognitive support without the sedation profile of benzos.

Nootropic
Evidence: Anecdotal

Selank: Russian-origin synthetic peptide. Anxiolytic and cognitive support without the sedation profile of benzos. Selank is a calm-but-clear nootropic.

FDA ⓘ
Not approved
WADA
Not banned
Typical dose
Intranasal: 250-500 mcg
Half-life ⓘ
~30 minutes (intranasal)
Route ⓘ
Intranasal spray (sub-q also used)
Schedule
1-3x daily
In plain English

Selank is a calm-but-clear nootropic. Russian-origin. Anxiolytic without the brain-fog of benzos. Intranasal spray, used as-needed for stress or focus.

Status & legalityWhat do these mean? →
Natty? ⓘ
Not natty
FDA ⓘ
Not approved

Not FDA approved. Approved in Russia.

Compounding ⓘ
Category 1

Compounding pharmacies may prepare under physician prescription (post Feb 2026 reclassification, pending formal FDA publication).

WADA ⓘ
Not listed
Prescribed ⓘ

Approved in Russia for anxiety. Not available by US prescription.

Who it's for

  • →Users with situational anxiety or cognitive load
  • →People wanting focus support without stimulants
  • →Anyone tapering off anxiolytics under provider guidance

What to expect

  1. Week 1

    Effect within hours of first dose for most users.

  2. Week 4

    Cumulative calming effect. No tolerance issues at standard doses.

  3. Week 8

    If cycled, second cycle hits as cleanly as the first.

Looking at Selank? Your next 3 steps

  1. 1Work out your exact dose

    Vial size + BAC water turns into the exact units to draw for Selank.

    Open calculator →
  2. 2See what to stack & monitor

    The companion supplements and the bloodwork worth tracking on this kind of protocol.

    Bloodwork guide →
  3. 3Save it & ask the Coach

    A free account saves your stack; membership adds the stack-aware AI Coach.

    Create free account →

How it works (mechanism)

Synthetic analog of tuftsin (an immunomodulatory peptide). Binds GABA-A receptors indirectly through neurotrophic factor BDNF modulation, producing anxiolytic effect without GABAergic sedation or dependence.

Dosing protocol

Members only

Stacks well with

Members only

Side effects

01Generally well tolerated
02Rare: mild fatigue early

When NOT to use

  • ⚠Pregnancy / nursing, no data

Common mistakes

  • • Treating it as immediate-relief like a benzo (it's gentler, builds over days)
  • • Confusing it with Semax (different mechanism, different use case)
  • • Storing the nasal spray at room temp long term

Community patterns

Members only
Free, no account needed

New to Selank? Grab the starter checklist.

Drop your email and we'll send the one-page first-cycle starter checklist, plus a heads-up if Selank changes legal status. No account needed.

No spam. No selling your email. Just the checklist and the occasional reclassification alert.

AI Coach, live sample
Members only
is 250mcg of bpc enough for a knee injury?
For a knee, 250 mcg sub-q daily is the standard working dose and a solid place to start. The trick with BPC is consistency, give it weeks, not days. Inject close to the joint, run it 4-6 weeks, and don't drop below 200 mcg, it tends to stop cracking the threshold reliably down there. If it hasn't moved at all by week 3, that's when adding TB-500 earns its place.
how much bac water for a 10mg reta vial?
3 mL is the standard play for a 10 mg reta vial. That's 3,333 mcg/mL, clean unit math across the titration: 2 mg = 60 units, 4 mg = 120 units, 6 mg = 180 units on a 100-unit insulin syringe. Run 2 mL instead if you want fewer, more concentrated shots (5,000 mcg/mL, so 2 mg = 40 units). Since most people titrate up over ~12 weeks, 3 mL keeps the numbers cleanest.
what should i track on bloodwork for tirzepatide?
Lipid panel, ALT/AST (liver enzymes), and an A1C, baseline before you start then every 3 months. If you've got metabolic-syndrome history, add fasting glucose and insulin so you can actually watch insulin sensitivity improve. You don't need a big hormone panel for a GLP-1.

Ask the Coach anything about Selank or your own stack. This is it working.

Trained only on Pepdex content. Does the dose math, flags interactions, knows your stack. Won't push vendors, won't pretend to be a doctor.

Get the Coach, $7.99/mo →

Frequently asked

What is Selank?+
Selank is a calm-but-clear nootropic. Russian-origin. Anxiolytic without the brain-fog of benzos. Intranasal spray, used as-needed for stress or focus.
Is Selank FDA approved?+
Not FDA approved. Approved in Russia.
Is Selank legal?+
Selank is not FDA-approved. It is sold by compounding pharmacies (with a prescription) and as "research only" by peptide vendors. Possession is generally not criminalized but distribution without authorization may be. Verify local laws.
Is Selank banned by WADA?+
Selank is not currently on the WADA prohibited list.
Are you still natty after taking Selank?+
No. Selank is a performance-enhancing peptide and would disqualify a strict natty claim.
Do doctors prescribe Selank?+
Approved in Russia for anxiety. Not available by US prescription.
What's the typical dose of Selank?+
Intranasal: 250-500 mcg, 1-3x daily. Sub-q: 100-250 mcg daily.
What are the side effects of Selank?+
Common side effects include: Generally well tolerated; Rare: mild fatigue early. Less common effects and full safety details are on the entry page.
How long until Selank starts working?+
Effect within hours of first dose for most users.
What can you stack with Selank?+
Common pairings: Semax for stacked anxiolytic + nootropic effect; Standalone. Full stacking protocol and timing on the entry page.
Where do people get Selank?+
Selank is most commonly sold by research-only peptide vendors and by compounding pharmacies (the latter requires a prescription). Pepdex is not a vendor, see /coa for how to verify a Certificate of Analysis before buying from any source, and /guides/scam-vendor-spotting for vendor red flags.
Selank vs Semax, which is better?+
Selank vs Semax: anxiolytic vs nootropic. Which to pick for which use case. Full head-to-head comparison: https://pepdex.co/compare/selank-vs-semax
Selank vs Oxytocin, which is better?+
Selank vs Oxytocin: anxiolytic without sedation vs social-bonding hormone. Different anxiety levers. Full head-to-head comparison: https://pepdex.co/compare/selank-vs-oxytocin

Head-to-head with Selank

Compare
Selank vs Semax →
Compare
Selank vs Oxytocin →

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