What is the half-life of Selank?
Selank has a reported half life of ~30 minutes (intranasal), given intranasal spray (sub-q also used). That is why it is typically dosed 1-3x daily. A shorter half life means more frequent dosing to keep blood levels steady, a longer one lets you space doses further apart.
Quick facts
- Half-life: ~30 minutes (intranasal)
- Route: Intranasal spray (sub-q also used)
- Typical schedule: 1-3x daily
- Cycle length: 2-4 weeks on, equal time off
References
- Peptide-based Anxiolytics: The Molecular Aspects of Heptapeptide Selank Biological Activity — Vyunova TV, Andreeva L, Shevchenko K, Myasoedov N. Protein and Peptide Letters, 2018
- Peptide Selank Enhances the Effect of Diazepam in Reducing Anxiety in Unpredictable Chronic Mild Stress Conditions in Rats — Kasian A, Kolomin T, Andreeva L, Bondarenko E, Myasoedov N, Slominsky P, Shadrina M. Behavioural Neurology, 2017
- Rapid and slow response during treatment of generalized anxiety disorder with peptide anxiolytic selank — European Psychiatry (EPA congress abstract P-1114), via ScienceDirect, 2012
Pepdex is an editorial reference, not medical advice. Peptides vary in legal and approval status by country, many are research compounds without full human safety data. Talk to a qualified clinician before starting anything.
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Last updated 2026-06-06.