What is the half-life of Cagrilintide?
Cagrilintide has a reported half life of ~7 days, given subcutaneous. That is why it is typically dosed once weekly. A shorter half life means more frequent dosing to keep blood levels steady, a longer one lets you space doses further apart.
Quick facts
- Half-life: ~7 days
- Route: Subcutaneous
- Typical schedule: Once weekly
- Cycle length: Open-ended
References
- Once-weekly cagrilintide for weight management, Phase 2 trial — Lau DCW et al., Lancet, 2021
- Coadministered Cagrilintide and Semaglutide in Adults with Overweight or Obesity (REDEFINE 1) — Garvey et al., N Engl J Med, 2025
- Safety, tolerability, pharmacokinetics, and pharmacodynamics of concomitant administration of multiple doses of cagrilintide with semaglutide 2.4 mg for weight management: a randomised, controlled, phase 1b trial — Enebo et al., Lancet, 2021
Pepdex is an editorial reference, not medical advice. Peptides vary in legal and approval status by country, many are research compounds without full human safety data. Talk to a qualified clinician before starting anything.
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Last updated 2026-06-06.