What is the half-life of Epitalon?
Epitalon has a reported half life of ~30 minutes, given subcutaneous. That is why it is typically dosed daily during the pulse. A shorter half life means more frequent dosing to keep blood levels steady, a longer one lets you space doses further apart.
Quick facts
- Half-life: ~30 minutes
- Route: Subcutaneous
- Typical schedule: Daily during the pulse
- Cycle length: 10-20 day pulses, 1-2x per year
References
- Epithalon peptide induces telomerase activity and telomere elongation in human somatic cells — Khavinson VKh, Bondarev IE, Butyugov AA, Bull Exp Biol Med, 2003
- Effect of peptide preparation epithalamin on circadian rhythm of epiphyseal melatonin-producing function in elderly people — Korkushko OV, Khavinson VKh, et al., Bull Exp Biol Med, 2004
- Overview of Epitalon-Highly Bioactive Pineal Tetrapeptide with Promising Properties — Araj SK, et al., Int J Mol Sci, 2025
Pepdex is an editorial reference, not medical advice. Peptides vary in legal and approval status by country, many are research compounds without full human safety data. Talk to a qualified clinician before starting anything.
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Last updated 2026-06-06.