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№ 015

Epitalon

Studied as an anti-aging and sleep-cycle peptide. A tetrapeptide derived from epithalamin, looked at for telomerase activation and circadian / pineal support, with limited human data.

Longevity
Evidence: Anecdotal

Epitalon: Studied as an anti-aging and sleep-cycle peptide. A tetrapeptide derived from epithalamin, looked at for telomerase activation and circadian / pineal support, with limited human data. Epitalon is a longevity-bucket peptide developed in Russia.

FDA ⓘ
Not approved
WADA
Not banned
Typical dose
5-10 mg sub-q daily for 10-20 consecutive days
Half-life ⓘ
~30 minutes
Route ⓘ
Subcutaneous
Schedule
Daily during the pulse
In plain English

Epitalon is a longevity-bucket peptide developed in Russia. Some lab data on telomere maintenance and circadian rhythm, but human evidence is limited. Run as a 10-20 day pulse once or twice a year, not continuously.

Status & legalityWhat do these mean? →
Natty? ⓘ
Not natty
FDA ⓘ
Not approved

Not FDA approved. Russian-origin research peptide.

Compounding ⓘ
Not classified

Not formally categorized in the FDA bulks lists.

WADA ⓘ
Not listed
Prescribed ⓘ

Used in some Russian clinical settings. Not part of conventional Western medicine.

Who it's for

  • →Users running longevity-focused stacks
  • →People with disrupted circadian rhythm or sleep architecture
  • →Older adults experimenting with anti-aging protocols

What to expect

  1. Week 1

    Sleep architecture often shifts within days.

  2. Week 4

    Pulse usually complete by this point.

  3. Week 8

    Off-cycle. Effects, if any, are subtle and long-tail.

Looking at Epitalon? Your next 3 steps

  1. 1Work out your exact dose

    Vial size + BAC water turns into the exact units to draw for Epitalon.

    Open calculator →
  2. 2See what to stack & monitor

    The companion supplements and the bloodwork worth tracking on this kind of protocol.

    Bloodwork guide →
  3. 3Save it & ask the Coach

    A free account saves your stack; membership adds the stack-aware AI Coach.

    Create free account →

How it works (mechanism)

Tetrapeptide derived from the larger pineal hormone epithalamin. Proposed mechanism is telomerase activation and circadian / pineal modulation. Russian preclinical and limited human data.

Dosing protocol

Members only

Stacks well with

Members only

Side effects

01Mild fatigue early in the pulse
02Vivid dreams
03Rare: headache

When NOT to use

  • ⚠Pregnancy / nursing
  • ⚠No data in active malignancy, avoid

Common mistakes

  • • Running it continuously instead of pulsing
  • • Expecting fast or visible effects (it isn't that kind of peptide)
  • • Stacking it with too many other experimental compounds and crediting Epitalon for everything
Free, no account needed

New to Epitalon? Grab the starter checklist.

Drop your email and we'll send the one-page first-cycle starter checklist, plus a heads-up if Epitalon changes legal status. No account needed.

No spam. No selling your email. Just the checklist and the occasional reclassification alert.

AI Coach, live sample
Members only
is 250mcg of bpc enough for a knee injury?
For a knee, 250 mcg sub-q daily is the standard working dose and a solid place to start. The trick with BPC is consistency, give it weeks, not days. Inject close to the joint, run it 4-6 weeks, and don't drop below 200 mcg, it tends to stop cracking the threshold reliably down there. If it hasn't moved at all by week 3, that's when adding TB-500 earns its place.
how much bac water for a 10mg reta vial?
3 mL is the standard play for a 10 mg reta vial. That's 3,333 mcg/mL, clean unit math across the titration: 2 mg = 60 units, 4 mg = 120 units, 6 mg = 180 units on a 100-unit insulin syringe. Run 2 mL instead if you want fewer, more concentrated shots (5,000 mcg/mL, so 2 mg = 40 units). Since most people titrate up over ~12 weeks, 3 mL keeps the numbers cleanest.
what should i track on bloodwork for tirzepatide?
Lipid panel, ALT/AST (liver enzymes), and an A1C, baseline before you start then every 3 months. If you've got metabolic-syndrome history, add fasting glucose and insulin so you can actually watch insulin sensitivity improve. You don't need a big hormone panel for a GLP-1.

Ask the Coach anything about Epitalon or your own stack. This is it working.

Trained only on Pepdex content. Does the dose math, flags interactions, knows your stack. Won't push vendors, won't pretend to be a doctor.

Get the Coach, $7.99/mo →

Frequently asked

What is Epitalon?+
Epitalon is a longevity-bucket peptide developed in Russia. Some lab data on telomere maintenance and circadian rhythm, but human evidence is limited. Run as a 10-20 day pulse once or twice a year, not continuously.
Is Epitalon FDA approved?+
Not FDA approved. Russian-origin research peptide.
Is Epitalon legal?+
Epitalon is not FDA-approved. It is sold by compounding pharmacies (with a prescription) and as "research only" by peptide vendors. Possession is generally not criminalized but distribution without authorization may be. Verify local laws.
Is Epitalon banned by WADA?+
Epitalon is not currently on the WADA prohibited list.
Are you still natty after taking Epitalon?+
No. Epitalon is a performance-enhancing peptide and would disqualify a strict natty claim.
Do doctors prescribe Epitalon?+
Used in some Russian clinical settings. Not part of conventional Western medicine.
What's the typical dose of Epitalon?+
5-10 mg sub-q daily for 10-20 consecutive days, repeated 1-2x per year.
What are the side effects of Epitalon?+
Common side effects include: Mild fatigue early in the pulse; Vivid dreams; Rare: headache. Less common effects and full safety details are on the entry page.
How long until Epitalon starts working?+
Sleep architecture often shifts within days.
What can you stack with Epitalon?+
Common pairings: Standalone is the norm. Full stacking protocol and timing on the entry page.
Where do people get Epitalon?+
Epitalon is most commonly sold by research-only peptide vendors and by compounding pharmacies (the latter requires a prescription). Pepdex is not a vendor, see /coa for how to verify a Certificate of Analysis before buying from any source, and /guides/scam-vendor-spotting for vendor red flags.
Epitalon vs Pinealon, which is better?+
Epitalon vs Pinealon: two Russian-origin longevity peptides targeting different aging pathways. Full head-to-head comparison: https://pepdex.co/compare/epitalon-vs-pinealon

Head-to-head with Epitalon

Compare
Epitalon vs Pinealon →

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