What is the half-life of GHK-Cu?
GHK-Cu has a reported half life of ~2 hours systemic, given sub-q (systemic) or topical (skin). That is why it is typically dosed daily. A shorter half life means more frequent dosing to keep blood levels steady, a longer one lets you space doses further apart.
Quick facts
- Half-life: ~2 hours systemic
- Route: Sub-q (systemic) or topical (skin)
- Typical schedule: Daily
- Cycle length: 4-6 weeks
References
- GHK and DNA: resetting the human genome to health — Pickart L et al., BioMed Res Int, 2014
- GHK Peptide as a Natural Modulator of Multiple Cellular Pathways in Skin Regeneration — Pickart L, Vasquez-Soltero JM, Margolina A; BioMed Research International; 2015
- The human tri-peptide GHK and tissue remodeling — Pickart L; Journal of Biomaterials Science, Polymer Edition; 2008
Pepdex is an editorial reference, not medical advice. Peptides vary in legal and approval status by country, many are research compounds without full human safety data. Talk to a qualified clinician before starting anything.
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Last updated 2026-06-06.