Is MK-677 (Ibutamoren) legal?
MK-677 (Ibutamoren) is not FDA approved as a finished drug. For drug-tested athletes it is WADA banned (S2). Not prescribed in conventional medicine. Sometimes offered by anti-aging clinics off-label.. Legal status depends on your country and changes over time. This reflects US status at the time of writing and is not legal or medical advice.
Regulatory status
- FDA: Not FDA approved. Reached Phase 2 trials, never approved.
- WADA: Banned (S2)
- Prescription: Not prescribed in conventional medicine. Sometimes offered by anti-aging clinics off-label.
References
- Effects of an oral ghrelin mimetic on body composition and clinical outcomes — Nass R et al., Ann Intern Med, 2008
- Two-month treatment of obese subjects with the oral growth hormone (GH) secretagogue MK-677 increases GH secretion, fat-free mass, and energy expenditure — Svensson J et al., Journal of Clinical Endocrinology & Metabolism, 1998
- LGD-4033 and MK-677 use impacts body composition, circulating biomarkers, and skeletal muscle androgenic hormone and receptor content: A case report — Cardaci TD et al., Experimental Physiology, 2022
Pepdex is an editorial reference, not medical advice. Peptides vary in legal and approval status by country, many are research compounds without full human safety data. Talk to a qualified clinician before starting anything.
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Last updated 2026-06-06.