What is the half-life of Sermorelin?
Sermorelin has a reported half life of ~10-20 minutes, given subcutaneous. That is why it is typically dosed once daily, typically before bed. A shorter half life means more frequent dosing to keep blood levels steady, a longer one lets you space doses further apart.
Quick facts
- Half-life: ~10-20 minutes
- Route: Subcutaneous
- Typical schedule: Once daily, typically before bed
- Cycle length: 12-24 weeks
References
- Sermorelin: a better approach to GH supplementation? — Walker RF, Clin Interv Aging, 2006
- Sermorelin: a review of its use in the diagnosis and treatment of children with idiopathic growth hormone deficiency — Prakash A & Goa KL, BioDrugs, 1999
- Treatment of radiation-induced growth hormone deficiency with growth hormone-releasing hormone — Ogilvy-Stuart AL et al., Clinical Endocrinology (Oxford), 1997
Pepdex is an editorial reference, not medical advice. Peptides vary in legal and approval status by country, many are research compounds without full human safety data. Talk to a qualified clinician before starting anything.
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Last updated 2026-06-06.