What is the half-life of Tesamorelin?
Tesamorelin has a reported half life of ~30 minutes, given subcutaneous. That is why it is typically dosed once daily. A shorter half life means more frequent dosing to keep blood levels steady, a longer one lets you space doses further apart.
Quick facts
- Half-life: ~30 minutes
- Route: Subcutaneous
- Typical schedule: Once daily
- Cycle length: 12-26 weeks typical
References
- Tesamorelin for HIV-associated lipodystrophy — Falutz J et al., NEJM, 2007
- Effect of tesamorelin on visceral fat and liver fat in HIV-infected patients with abdominal fat accumulation: a randomized clinical trial — Stanley TL et al., JAMA, 2014
- Effects of tesamorelin (TH9507), a growth hormone-releasing factor analog, in HIV-infected patients with excess abdominal fat: a pooled analysis of two multicenter, double-blind placebo-controlled phase 3 trials with safety extension data — Falutz J et al., Journal of Clinical Endocrinology & Metabolism, 2010
Pepdex is an editorial reference, not medical advice. Peptides vary in legal and approval status by country, many are research compounds without full human safety data. Talk to a qualified clinician before starting anything.
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Last updated 2026-06-06.