What is Tesamorelin used for?
Tesamorelin is most commonly used for users targeting visceral (deep abdominal) fat specifically; older adults wanting GH-axis support without HGH; people with elevated visceral fat on DEXA. Used to shrink deep belly fat. A GHRH analog that's FDA-approved for HIV-associated lipodystrophy and used off-label for visceral fat reduction. Human evidence for Tesamorelin is limited, so these are the goals people pursue with it, not guaranteed outcomes.
What people use Tesamorelin for
- Users targeting visceral (deep abdominal) fat specifically
- Older adults wanting GH-axis support without HGH
- People with elevated visceral fat on DEXA
References
- Tesamorelin for HIV-associated lipodystrophy — Falutz J et al., NEJM, 2007
- Effect of tesamorelin on visceral fat and liver fat in HIV-infected patients with abdominal fat accumulation: a randomized clinical trial — Stanley TL et al., JAMA, 2014
- Effects of tesamorelin (TH9507), a growth hormone-releasing factor analog, in HIV-infected patients with excess abdominal fat: a pooled analysis of two multicenter, double-blind placebo-controlled phase 3 trials with safety extension data — Falutz J et al., Journal of Clinical Endocrinology & Metabolism, 2010
Pepdex is an editorial reference, not medical advice. Peptides vary in legal and approval status by country, many are research compounds without full human safety data. Talk to a qualified clinician before starting anything.
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Last updated 2026-06-15.