Is VIP (Vasoactive Intestinal Peptide) legal?
VIP (Vasoactive Intestinal Peptide) is not FDA approved as a finished drug. For drug-tested athletes it is not on the WADA prohibited list. Yes by some functional-medicine and CIRS-literate providers, via compounding pharmacies.. Legal status depends on your country and changes over time. This reflects US status at the time of writing and is not legal or medical advice.
Regulatory status
- FDA: Not FDA approved as a drug. Used in compounded form in CIRS clinical protocols (Shoemaker).
- WADA: Not listed
- Prescription: Yes by some functional-medicine and CIRS-literate providers, via compounding pharmacies.
References
- Vasoactive intestinal peptide (VIP) and inflammation, review — Delgado M & Ganea D, Amino Acids, 2013
- Research advances of vasoactive intestinal peptide in the pathogenesis of ulcerative colitis by regulating interleukin-10 expression in regulatory B cells — Sun X et al., World Journal of Gastroenterology, 2020
- Therapeutic Potential of Vasoactive Intestinal Peptide and its Derivative Stearyl-Norleucine-VIP in Inflammation-Induced Osteolysis — Eger M et al., Frontiers in Pharmacology, 2021
Pepdex is an editorial reference, not medical advice. Peptides vary in legal and approval status by country, many are research compounds without full human safety data. Talk to a qualified clinician before starting anything.
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Last updated 2026-06-06.