What is VIP (Vasoactive Intestinal Peptide) used for?
VIP (Vasoactive Intestinal Peptide) is most commonly used for users with CIRS or mold-illness contexts under medical guidance; chronic inflammatory conditions; post-biotoxin-exposure recovery (well-defined Shoemaker protocol). Endogenous 28-amino-acid neuropeptide. Modulates immune function and inflammation. Used in CIRS (chronic inflammatory response syndrome) protocols and biotoxin exposure recovery, popularized by Dr. Ritchie Shoemaker. Human evidence for VIP (Vasoactive Intestinal Peptide) is limited, so these are the goals people pursue with it, not guaranteed outcomes.
What people use VIP (Vasoactive Intestinal Peptide) for
- Users with CIRS or mold-illness contexts under medical guidance
- Chronic inflammatory conditions
- Post-biotoxin-exposure recovery (well-defined Shoemaker protocol)
References
- Vasoactive intestinal peptide (VIP) and inflammation, review — Delgado M & Ganea D, Amino Acids, 2013
- Research advances of vasoactive intestinal peptide in the pathogenesis of ulcerative colitis by regulating interleukin-10 expression in regulatory B cells — Sun X et al., World Journal of Gastroenterology, 2020
- Therapeutic Potential of Vasoactive Intestinal Peptide and its Derivative Stearyl-Norleucine-VIP in Inflammation-Induced Osteolysis — Eger M et al., Frontiers in Pharmacology, 2021
Pepdex is an editorial reference, not medical advice. Peptides vary in legal and approval status by country, many are research compounds without full human safety data. Talk to a qualified clinician before starting anything.
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Last updated 2026-06-15.