What is HCG (Human Chorionic Gonadotropin) used for?
HCG (Human Chorionic Gonadotropin) is most commonly used for men running TRT who want to preserve testicular size and fertility; post-cycle users restarting their HPG axis; fertility patients (under physician supervision). Used clinically to boost fertility and restart the body's own testosterone production after a suppressive cycle. It's a glycoprotein hormone that works by mimicking LH at the testicular Leydig cell. Human evidence for HCG (Human Chorionic Gonadotropin) is limited, so these are the goals people pursue with it, not guaranteed outcomes.
What people use HCG (Human Chorionic Gonadotropin) for
- Men running TRT who want to preserve testicular size and fertility
- Post-cycle users restarting their HPG axis
- Fertility patients (under physician supervision)
References
- Low-Dose Human Chorionic Gonadotropin Maintains Intratesticular Testosterone in Normal Men with Testosterone-Induced Gonadotropin Suppression — Coviello AD, Matsumoto AM, Bremner WJ, et al. — Journal of Clinical Endocrinology & Metabolism, 2005;90(5):2595-2602
- Concomitant intramuscular human chorionic gonadotropin preserves spermatogenesis in men undergoing testosterone replacement therapy — Hsieh TC, Pastuszak AW, Hwang K, Lipshultz LI — Journal of Urology, 2013;189(2):647-50
Pepdex is an editorial reference, not medical advice. Peptides vary in legal and approval status by country, many are research compounds without full human safety data. Talk to a qualified clinician before starting anything.
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Last updated 2026-06-15.