What is the half-life of Ipamorelin?
Ipamorelin has a reported half life of ~2 hours, given subcutaneous. That is why it is typically dosed 1-3x daily. A shorter half life means more frequent dosing to keep blood levels steady, a longer one lets you space doses further apart.
Quick facts
- Half-life: ~2 hours
- Route: Subcutaneous
- Typical schedule: 1-3x daily
- Cycle length: 8-12 weeks on, 4 weeks off
References
- Ipamorelin, the first selective GH secretagogue — Raun K et al., Eur J Endocrinol, 1998
- Prospective, randomized, controlled, proof-of-concept study of the ghrelin mimetic ipamorelin for the management of postoperative ileus in bowel resection patients — Beck DE et al., International Journal of Colorectal Disease, 2014
- Injectable Peptides in Sports Medicine: A Structured Narrative Review of Evidence, Safety, and Antidoping Implications — Villegas Meza AD et al., JBJS Reviews, 2026
Pepdex is an editorial reference, not medical advice. Peptides vary in legal and approval status by country, many are research compounds without full human safety data. Talk to a qualified clinician before starting anything.
More on Ipamorelin
Last updated 2026-06-06.