pepdex
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006

Ipamorelin

Selective GH secretagogue. Bumps natural GH pulses without hitting cortisol or prolactin.

GH-axis
Evidence: Limited
Half-life
~2 hours
Route
Subcutaneous
Cycle
8-12 weeks on, 4 weeks off
Schedule
1-3x daily
In plain English

Ipamorelin gently nudges your body to release more of its own growth hormone — without the side-effect baggage of injecting actual HGH. People run it for sleep, recovery, and slow body-comp shifts. Tiny doses, multiple times a day.

Status & legality
Natty?
Not natty
FDA
Not approved

Not FDA approved.

Compounding
Category 1

Compounding pharmacies may prepare under physician prescription (post Feb 2026 reclassification, pending formal FDA publication).

WADA
Banned (S2)
Prescribed

Some anti-aging and longevity clinics prescribe via compounding pharmacies, off-label.

Who it's for

  • Users wanting GH benefits without the bloat / sides of HGH
  • Sleep / recovery focused stacks
  • Beginners to GH-class peptides

What to expect

  1. Week 1

    Deeper sleep within the first few nights.

  2. Week 4

    Recovery improvement noticeable. Skin/hair starts looking better.

  3. Week 8

    Cumulative effect on body composition for users in a clean diet.

Dosing protocol

100-300 mcg sub-q, 1-3x daily. Pre-bed dose is the most important pulse.

Stacks well with

CJC-1295 (no DAC) for synergistic GH pulse
Standalone for sleep focus

Side effects

01Head-rush at injection
02Mild hunger pulse 30 min post-dose
03Tingling in hands rarely

When NOT to use

  • Active malignancy
  • Pregnancy / nursing

Bloodwork to monitor

  • IGF-1 baseline + at week 8

Common mistakes

  • Eating within 30 min of injection (food blunts the GH pulse)
  • Skipping the pre-bed dose
  • Not cycling off

Educational only. User-specific dosing is between you and a qualified provider.

Frequently asked

What is Ipamorelin?+
Ipamorelin gently nudges your body to release more of its own growth hormone — without the side-effect baggage of injecting actual HGH. People run it for sleep, recovery, and slow body-comp shifts. Tiny doses, multiple times a day.
Is Ipamorelin FDA approved?+
Not FDA approved.
Is Ipamorelin banned by WADA?+
Ipamorelin is on the WADA prohibited list under Banned (S2).
Are you still natty after taking Ipamorelin?+
No. Ipamorelin is a performance-enhancing peptide and would disqualify a strict natty claim.
Do doctors prescribe Ipamorelin?+
Some anti-aging and longevity clinics prescribe via compounding pharmacies, off-label.
What's the typical dose of Ipamorelin?+
100-300 mcg sub-q, 1-3x daily. Pre-bed dose is the most important pulse.
What are the side effects of Ipamorelin?+
Common side effects include: Head-rush at injection; Mild hunger pulse 30 min post-dose; Tingling in hands rarely. Less common effects and full safety details are on the entry page.
How long until Ipamorelin starts working?+
Deeper sleep within the first few nights.