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№ 007

CJC-1295 (no DAC)

Pairs with Ipamorelin to amplify your natural growth-hormone pulses. A GHRH analog whose 'no-DAC' version stays short-acting on purpose.

GH-axis
Evidence: Limited

CJC-1295 (no DAC): Pairs with Ipamorelin to amplify your natural growth-hormone pulses. A GHRH analog whose 'no-DAC' version stays short-acting on purpose. CJC-1295 (the 'no-DAC' version) is the partner peptide to Ipamorelin.

FDA ⓘ
Not approved
WADA
Banned
Typical dose
100 mcg sub-q
Half-life ⓘ
~30 min (no DAC)
Route ⓘ
Subcutaneous
Schedule
1-3x daily, paired with Ipamorelin
In plain English

CJC-1295 (the 'no-DAC' version) is the partner peptide to Ipamorelin. Together they push a stronger natural GH pulse. Always paired, never run alone in this protocol.

Status & legalityWhat do these mean? →
Natty? ⓘ
Not natty
FDA ⓘ
Not approved

Not FDA approved.

Compounding ⓘ
Category 1

Compounding pharmacies may prepare under physician prescription (post Feb 2026 reclassification, pending formal FDA publication).

WADA ⓘ
Banned (S2)
Prescribed ⓘ

Some longevity clinics prescribe via compounding pharmacies, off-label.

Before you start

Wear a CGM the first 14 days.

GH spikes can transiently raise glucose; verify it normalizes. A two-week sensor (~$80, OTC, no prescription) tells you more about how YOUR body is responding to CJC-1295 (no DAC) than any protocol guide can. Most users wear one and don't again. The first cycle is the one that matters.

Get a CGM →

Who it's for

  • →Users stacking with Ipamorelin (the canonical pair)
  • →People wanting GH benefits while preserving the natural pulse rhythm

What to expect

  1. Week 1

    Stronger GH pulse felt as deeper sleep, more vivid dreams.

  2. Week 4

    Recovery and skin improvements compound.

  3. Week 8

    IGF-1 measurably higher in most users.

Looking at CJC-1295 (no DAC)? Your next 3 steps

  1. 1Work out your exact dose

    Vial size + BAC water turns into the exact units to draw for CJC-1295 (no DAC).

    Open calculator →
  2. 2See what to stack & monitor

    The companion supplements and the bloodwork worth tracking on this kind of protocol.

    Bloodwork guide →
  3. 3Save it & ask the Coach

    A free account saves your stack; membership adds the stack-aware AI Coach.

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How it works (mechanism)

Synthetic GHRH analog (no-DAC version). Binds the growth hormone-releasing hormone receptor on the pituitary, signaling 'release GH'. Short half-life keeps natural GH pulses distinct rather than smoothing them into a flat elevation.

Dosing protocol

Members only

Stacks well with

Members only

Stack essentials

Members only

Side effects

01Head-rush
02Brief facial flush
03Hunger pulse

When NOT to use

  • ⚠Active malignancy
  • ⚠Pregnancy / nursing

Bloodwork to monitor

  • • IGF-1 baseline + week 8

Common mistakes

  • • Using the DAC version expecting the same pulse profile (it's not the same)
  • • Eating right after the dose
  • • Skipping the cycle break

Drug & supplement interactions

  • ⚠Eating within 30 minutes blunts GH pulse
  • ⚠Limited documented drug interactions

The Pepdex take

The 'no-DAC' specification is the whole game. With-DAC keeps GH levels elevated continuously which flatlines the natural pulse rhythm, that's not what you want. If a vendor sells 'CJC-1295' without specifying no-DAC, assume it's DAC and pass. Pair with Ipamorelin pre-bed and forget about it. Cycle 8-12 weeks on, 4 weeks off.

Community patterns

Members only
Free, no account needed

New to CJC-1295 (no DAC)? Grab the starter checklist.

Drop your email and we'll send the one-page first-cycle starter checklist, plus a heads-up if CJC-1295 (no DAC) changes legal status. No account needed.

No spam. No selling your email. Just the checklist and the occasional reclassification alert.

AI Coach, live sample
Members only
is 250mcg of bpc enough for a knee injury?
For a knee, 250 mcg sub-q daily is the standard working dose and a solid place to start. The trick with BPC is consistency, give it weeks, not days. Inject close to the joint, run it 4-6 weeks, and don't drop below 200 mcg, it tends to stop cracking the threshold reliably down there. If it hasn't moved at all by week 3, that's when adding TB-500 earns its place.
how much bac water for a 10mg reta vial?
3 mL is the standard play for a 10 mg reta vial. That's 3,333 mcg/mL, clean unit math across the titration: 2 mg = 60 units, 4 mg = 120 units, 6 mg = 180 units on a 100-unit insulin syringe. Run 2 mL instead if you want fewer, more concentrated shots (5,000 mcg/mL, so 2 mg = 40 units). Since most people titrate up over ~12 weeks, 3 mL keeps the numbers cleanest.
what should i track on bloodwork for tirzepatide?
Lipid panel, ALT/AST (liver enzymes), and an A1C, baseline before you start then every 3 months. If you've got metabolic-syndrome history, add fasting glucose and insulin so you can actually watch insulin sensitivity improve. You don't need a big hormone panel for a GLP-1.

Ask the Coach anything about CJC-1295 (no DAC) or your own stack. This is it working.

Trained only on Pepdex content. Does the dose math, flags interactions, knows your stack. Won't push vendors, won't pretend to be a doctor.

Get the Coach, $7.99/mo →

Frequently asked

What is CJC-1295 (no DAC)?+
CJC-1295 (the 'no-DAC' version) is the partner peptide to Ipamorelin. Together they push a stronger natural GH pulse. Always paired, never run alone in this protocol.
Is CJC-1295 (no DAC) FDA approved?+
Not FDA approved.
Is CJC-1295 (no DAC) legal?+
CJC-1295 (no DAC) is not FDA-approved. It is sold by compounding pharmacies (with a prescription) and as "research only" by peptide vendors. Possession is generally not criminalized but distribution without authorization may be. Verify local laws.
Is CJC-1295 (no DAC) banned by WADA?+
CJC-1295 (no DAC) is on the WADA prohibited list under Banned (S2).
Are you still natty after taking CJC-1295 (no DAC)?+
No. CJC-1295 (no DAC) is a performance-enhancing peptide and would disqualify a strict natty claim.
Do doctors prescribe CJC-1295 (no DAC)?+
Some longevity clinics prescribe via compounding pharmacies, off-label.
What's the typical dose of CJC-1295 (no DAC)?+
100 mcg sub-q, 1-3x daily, paired 1:1 with Ipamorelin.
What are the side effects of CJC-1295 (no DAC)?+
Common side effects include: Head-rush; Brief facial flush; Hunger pulse. Less common effects and full safety details are on the entry page.
How long until CJC-1295 (no DAC) starts working?+
Stronger GH pulse felt as deeper sleep, more vivid dreams.
What can you stack with CJC-1295 (no DAC)?+
Common pairings: Ipamorelin (always); MK-677 if oral GH-secretagogue tolerance is fine (off-label). Full stacking protocol and timing on the entry page.
Where do people get CJC-1295 (no DAC)?+
CJC-1295 (no DAC) is most commonly sold by research-only peptide vendors and by compounding pharmacies (the latter requires a prescription). Pepdex is not a vendor, see /coa for how to verify a Certificate of Analysis before buying from any source, and /guides/scam-vendor-spotting for vendor red flags.
CJC-1295 (no DAC) vs Ipamorelin, which is better?+
Ipamorelin vs CJC-1295: how they differ mechanistically and why the standard protocol pairs them. Full head-to-head comparison: https://pepdex.co/compare/ipamorelin-vs-cjc-1295
CJC-1295 (no DAC) vs Sermorelin, which is better?+
CJC-1295 (no DAC) vs Sermorelin: modified vs unmodified GHRH analogs. Half-life, dosing frequency, real-world use. Full head-to-head comparison: https://pepdex.co/compare/cjc-1295-vs-sermorelin

Head-to-head with CJC-1295 (no DAC)

Compare
CJC-1295 (no DAC) vs Ipamorelin →
Compare
CJC-1295 (no DAC) vs Sermorelin →

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