What is the half-life of TB-500?
TB-500 has a reported half life of ~2-3 days, given subcutaneous or intramuscular. That is why it is typically dosed loading 2x/wk → maintenance 1x/wk. A shorter half life means more frequent dosing to keep blood levels steady, a longer one lets you space doses further apart.
Quick facts
- Half-life: ~2-3 days
- Route: Subcutaneous or intramuscular
- Typical schedule: Loading 2x/wk → maintenance 1x/wk
- Cycle length: 8-12 weeks total
References
- Thymosin β4: a novel regenerative pharmacological agent — Goldstein AL & Kleinman HK, Ann NY Acad Sci, 2012
- Thymosin beta4 activates integrin-linked kinase and promotes cardiac cell migration, survival and cardiac repair — Bock-Marquette I, Saxena A, White MD, Dimaio JM, Srivastava D — Nature, 2004
Pepdex is an editorial reference, not medical advice. Peptides vary in legal and approval status by country, many are research compounds without full human safety data. Talk to a qualified clinician before starting anything.
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Last updated 2026-06-06.