pepdex
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№ 010

MT-2 (Melanotan II)

Less selective alpha-MSH analog. Stronger pigmentation than MT-1, but also hits libido and brings rougher side effects.

Pigment
Evidence: Limited
Half-life
~30 minutes
Route
Subcutaneous
Cycle
Loading 1-2 wks, then maintenance
Schedule
Daily loading → 2-3x weekly maintenance
In plain English

MT-2 is the more potent (and rougher) sibling of MT-1. Stronger pigmentation but harder side-effect profile, including unwanted libido effects. Most people who tried MT-2 first migrate to MT-1 for cleaner results.

Status & legality
Natty?
Not natty
FDA
Not approved

Not FDA approved. Afamelanotide (MT-1) is the approved analog.

Compounding
Not classified

Not formally categorized in the FDA bulks lists.

WADA
Not listed
Prescribed

Not prescribed in conventional medicine.

Who it's for

  • →Users wanting deeper pigmentation than MT-1 delivers
  • →People who specifically want the libido side effect
  • →Anyone who tolerated the nausea/flush profile in past use

What to expect

  1. Week 1

    Strong nausea early, facial flush, spontaneous erections in male users.

  2. Week 4

    Visible pigmentation if UV exposure paired. Side effects fade.

  3. Week 8

    Maintenance dosing holds tan with weekly use.

Dosing protocol

Loading: 250-500 mcg sub-q daily for 1-2 weeks. Maintenance: 250-500 mcg, 2-3x weekly. Pair with UV exposure.

Stacks well with

Standalone
PT-141 if libido is the primary goal (different mechanism)

Side effects

01Nausea (more pronounced than MT-1)
02Facial flushing
03Spontaneous erections / increased libido
04Appetite suppression
05Mole / freckle darkening — mole-map first
06Headache

When NOT to use

  • ⚠Personal history of melanoma
  • ⚠Atypical mole syndrome
  • ⚠Pregnancy / nursing

Common mistakes

  • • Starting at full dose instead of titrating up — nausea hits hard
  • • Skipping the mole-map baseline
  • • Confusing dosing with MT-1 (different side effect profile)

Educational only. User-specific dosing is between you and a qualified provider.

Frequently asked

What is MT-2 (Melanotan II)?+
MT-2 is the more potent (and rougher) sibling of MT-1. Stronger pigmentation but harder side-effect profile, including unwanted libido effects. Most people who tried MT-2 first migrate to MT-1 for cleaner results.
Is MT-2 (Melanotan II) FDA approved?+
Not FDA approved. Afamelanotide (MT-1) is the approved analog.
Is MT-2 (Melanotan II) banned by WADA?+
MT-2 (Melanotan II) is not currently on the WADA prohibited list.
Are you still natty after taking MT-2 (Melanotan II)?+
No. MT-2 (Melanotan II) is a performance-enhancing peptide and would disqualify a strict natty claim.
Do doctors prescribe MT-2 (Melanotan II)?+
Not prescribed in conventional medicine.
What's the typical dose of MT-2 (Melanotan II)?+
Loading: 250-500 mcg sub-q daily for 1-2 weeks. Maintenance: 250-500 mcg, 2-3x weekly. Pair with UV exposure.
What are the side effects of MT-2 (Melanotan II)?+
Common side effects include: Nausea (more pronounced than MT-1); Facial flushing; Spontaneous erections / increased libido; Appetite suppression. Less common effects and full safety details are on the entry page.
How long until MT-2 (Melanotan II) starts working?+
Strong nausea early, facial flush, spontaneous erections in male users.