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№ 037

Follistatin 344

A compound aimed at unlocking muscle growth by releasing the body's natural brake on it. A myostatin antagonist that binds and neutralizes myostatin, the negative regulator of muscle growth. Theoretical muscle-growth signal, limited human data.

GH-axis
Evidence: Anecdotal

Follistatin 344: A compound aimed at unlocking muscle growth by releasing the body's natural brake on it. A myostatin antagonist that binds and neutralizes myostatin, the negative regulator of muscle growth. Theoretical muscle-growth signal, limited human data. Follistatin 344 blocks myostatin, the protein that puts a ceiling on how much muscle you can build.

FDA ⓘ
Not approved
WADA
Banned
Typical dose
100-300 mcg sub-q daily for 10-30 days
Half-life ⓘ
~hours (poorly characterized)
Route ⓘ
Subcutaneous
Schedule
Daily
In plain English

Follistatin 344 blocks myostatin, the protein that puts a ceiling on how much muscle you can build. Theoretically removing the brake means more muscle growth. Real human data is very limited. Treat as experimental, run short cycles only.

Status & legalityWhat do these mean? →
Natty? ⓘ
Not natty

Myostatin antagonism is universally banned in tested sport.

FDA ⓘ
Not approved

Not FDA approved.

Compounding ⓘ
Not classified

Not formally categorized in the FDA bulks lists.

WADA ⓘ
Banned (S4)

S4 Hormone and Metabolic Modulators, myostatin inhibitors are explicitly listed.

Prescribed ⓘ

Not prescribed in conventional medicine.

Who it's for

  • →Bodybuilders / lifters experimenting with muscle-growth pathways
  • →Researchers studying myostatin biology

What to expect

  1. Week 1

    Anecdotal pumps and fullness reports.

  2. Week 4

    Subjective effects peak around here for responders. Cycle endpoint, stop.

  3. Week 8

    Off-cycle. No long-cycle data exists.

Looking at Follistatin 344? Your next 3 steps

  1. 1Work out your exact dose

    Vial size + BAC water turns into the exact units to draw for Follistatin 344.

    Open calculator →
  2. 2See what to stack & monitor

    The companion supplements and the bloodwork worth tracking on this kind of protocol.

    Bloodwork guide →
  3. 3Save it & ask the Coach

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How it works (mechanism)

Glycoprotein that binds and neutralizes myostatin. Different mechanism from ACE-031, direct ligand-binding rather than receptor-decoy. Theoretically permits increased muscle growth by removing the negative regulator.

Dosing protocol

Members only

Stacks well with

Members only

Side effects

01Limited human safety data
02Theoretical: cardiac and tendon issues with chronic strong myostatin suppression
03Injection-site irritation

When NOT to use

  • ⚠Anyone risk-averse to limited human data
  • ⚠Pregnancy / nursing
  • ⚠Active malignancy

Common mistakes

  • • Running it longer than 30 days without safety data
  • • Treating it as steroid-equivalent (it isn't)
  • • Stacking with too many other compounds and crediting Follistatin for everything
Free, no account needed

New to Follistatin 344? Grab the starter checklist.

Drop your email and we'll send the one-page first-cycle starter checklist, plus a heads-up if Follistatin 344 changes legal status. No account needed.

No spam. No selling your email. Just the checklist and the occasional reclassification alert.

AI Coach, live sample
Members only
is 250mcg of bpc enough for a knee injury?
For a knee, 250 mcg sub-q daily is the standard working dose and a solid place to start. The trick with BPC is consistency, give it weeks, not days. Inject close to the joint, run it 4-6 weeks, and don't drop below 200 mcg, it tends to stop cracking the threshold reliably down there. If it hasn't moved at all by week 3, that's when adding TB-500 earns its place.
how much bac water for a 10mg reta vial?
3 mL is the standard play for a 10 mg reta vial. That's 3,333 mcg/mL, clean unit math across the titration: 2 mg = 60 units, 4 mg = 120 units, 6 mg = 180 units on a 100-unit insulin syringe. Run 2 mL instead if you want fewer, more concentrated shots (5,000 mcg/mL, so 2 mg = 40 units). Since most people titrate up over ~12 weeks, 3 mL keeps the numbers cleanest.
what should i track on bloodwork for tirzepatide?
Lipid panel, ALT/AST (liver enzymes), and an A1C, baseline before you start then every 3 months. If you've got metabolic-syndrome history, add fasting glucose and insulin so you can actually watch insulin sensitivity improve. You don't need a big hormone panel for a GLP-1.

Ask the Coach anything about Follistatin 344 or your own stack. This is it working.

Trained only on Pepdex content. Does the dose math, flags interactions, knows your stack. Won't push vendors, won't pretend to be a doctor.

Get the Coach, $7.99/mo →

Frequently asked

What is Follistatin 344?+
Follistatin 344 blocks myostatin, the protein that puts a ceiling on how much muscle you can build. Theoretically removing the brake means more muscle growth. Real human data is very limited. Treat as experimental, run short cycles only.
Is Follistatin 344 FDA approved?+
Not FDA approved.
Is Follistatin 344 legal?+
Follistatin 344 is not FDA-approved. It is sold by compounding pharmacies (with a prescription) and as "research only" by peptide vendors. Possession is generally not criminalized but distribution without authorization may be. Verify local laws.
Is Follistatin 344 banned by WADA?+
Follistatin 344 is on the WADA prohibited list under Banned (S4). S4 Hormone and Metabolic Modulators, myostatin inhibitors are explicitly listed.
Are you still natty after taking Follistatin 344?+
No. Myostatin antagonism is universally banned in tested sport.
Do doctors prescribe Follistatin 344?+
Not prescribed in conventional medicine.
What's the typical dose of Follistatin 344?+
100-300 mcg sub-q daily for 10-30 days. No long-cycle protocol exists.
What are the side effects of Follistatin 344?+
Common side effects include: Limited human safety data; Theoretical: cardiac and tendon issues with chronic strong myostatin suppression; Injection-site irritation. Less common effects and full safety details are on the entry page.
How long until Follistatin 344 starts working?+
Anecdotal pumps and fullness reports.
What can you stack with Follistatin 344?+
Common pairings: Standalone, pairing it makes signal harder to read. Full stacking protocol and timing on the entry page.
Where do people get Follistatin 344?+
Follistatin 344 is most commonly sold by research-only peptide vendors and by compounding pharmacies (the latter requires a prescription). Pepdex is not a vendor, see /coa for how to verify a Certificate of Analysis before buying from any source, and /guides/scam-vendor-spotting for vendor red flags.

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